FGL

Neuro degeneration repair FGL FG Loop peptide is a 15 amino acid, synthetic mimetic of the Neural Cell Adhesion Molecule NCAM that acts as a potent fibroblast growth factor receptor 1 FGFR1 agonist. It promotes neuronal survival, neurite outgrowth, and synaptic plasticity, with significant research into treating neurodegenerative diseases, such as Alzheimer's, and improving cognitive function. Mechanism of Action: FGL binds to and activates FGFR1, which stimulates intracellular signaling pathways involved in neuronal survival and differentiation. Therapeutic Potential: It shows promise for neuroprotective, neurotrophic, and anti inflammatory effects. Studies suggest it can improve memory, reduce anxiety, and counteract depression like behaviour in animal models. Research Areas: Primarily researched for Alzheimer's disease, dementia, and as a potential regenerative treatment after stroke, where it may help mobilize endogenous neural stem cells.