IGF 1LR3 - 1mg

Body building muscle hypertrophy a synthetic analog of insulin like growth factor 1 IGF 1 with an N terminal 13 amino acid extension and an Arg →Gly substitution at position 3. That modification greatly reduces binding to IGF binding proteins, increasing bioavailability and potency versus native IGF 1. Mechanism: activates the IGF 1 receptor a receptor tyrosine kinase , stimulating PI3K Akt and MAPK pathways → increased cell survival, protein synthesis, proliferation, and glucose uptake. Stronger and longer lasting receptor activation vs native IGF 1. Common research uses: cell culture and animal studies of growth, muscle hypertrophy, tissue repair regeneration, cancer biology, and metabolic signaling.